何汉平教授
  • 作者:佚名    发布日期:2013-03-28    点击率:

   名:何汉平

出生年月:1976.12

职称职务:教授,湖北省“楚天学者计划”楚天学子,硕士生、博士生导师

专业方向:有机化学 化学生物学

电话: 15827220426

Emailhehanping@hubu.edu.cn

                                                                             

研究领域与兴趣:

1) 生物传感研究

2)核酸特殊序列的分析和检测

3)化学探针的合成与研究

                                                   

教育与研究经历:

2016.07~         湖北大学化学化工学院 教授

2010.07~ 2016.06   湖北大学化学化工学院 副教授

2008.04~2010.03  日本大阪大学产业科学研究所 特任研究员

2006.04~2008.03  日本学术振兴会JSPS特别研究员 大阪大学产业科学研究所

2006.01~2006.03  日本京都大学国际融合交流中心 特别研究员

2000.09~2005.11  武汉大学化学与分子科学学院 获博士学位 有机化学

1996.09~2000.07   湖北大学化学系获学士学位,应用化学专业

                                                   

教学情况:

有机化学、有机化学实验、化学生物学、现代有机合成

                                                   

承担项目与课题:

1)       国家自然科学基金面上项目,用于三核苷酸重复疾病早期诊断的高灵敏电化学生物传感体系的构建和应用研究(21575035),主持;

2)       国家自然科学基金青年基金,新型萘啶衍生物作为核酸特定序列识别分子的研究(21002024), 主持;

3)       湖北省科技厅对外科技合作类项目(2015BHE025),纳米核酸探针在神经遗传病基因检测和基因治疗中的应用,主持;

4)       湖北省教育厅科学技术研究计划重点项目(D20131007),主持;

5)       湖北省自然科学基金创新群体项目(2011CDA111),核心成员;

6)     湖北省高等学校优秀中青年科技创新团队计划(T201101),核心成员。

                                                   

代表性成果:

1        Jiao Li, Yalan Liu, Xiaoqian Zhu, Gang Chang*, Hanping He*, Xiuhua Zhang, and Shengfu Wang, A novel electrochemical biosensor based on a double-signal technique for d(CAG)n trinucleotide repeats. ACS Appl. Mater. Interfaces, 2017, 9 (50), pp 4423144240. (IF:8.097,一区Top )

2        Xiaoqian Zhu, Jiao Li, Hanping He*, Min Huang, Xiuhua Zhang Shengfu WangApplication of nanomaterials in the bioanalytical detection of disease-related geneBiosensors and Bioelectronics, 2015,2015(74),113-133. (IF:8.173,一区Top )

3        Hanping He, Jingping Xia, Xiaoqian Peng, Gang Chang, Xiuhua Zhang, Yafen Wang, Kazuhiko Nakatani, Zhaowen Lou, Shengfu Wang, Facile electrochemical biosensor based on a new bifunctional probe for label-free detection of CGG trinucleotide repeat, Biosensors and Bioelectronics, 2013, 49, 282-289. (IF: IF:8.173,一区Top)

4        Hanping He, Jingping Xia, Gang Chang, Xiaoqian Peng, Zhaowen Lou, Kazuhiko Nakatani, Xiang Zhou, Shengfu Wang, Selective recognition of G-G mismatch using the Double Functional Probe with electrochemical active ferrocenyl, Biosensors and Bioelectronics, 2013, 42, 36-40. (IF: 8.173,一区Top)

5        Hanping He*, Xiaoqian Peng, Min Huang, Xiuhua Zhang, Gang Chang, Shengfu Wang, Electrochemical impedance sensor based on small molecule modified Au electrode for the recognition of a trinucleotide repeat, Analyst, 2014, 139, 5482-5487. (IF: 4.107,二区).

6        Yalan Liu, Jiao Li, Gang Chang, Ruizhi ZhuHanping He*, Xiuhua Zhang, Shengfu Wang. A novel Electrochemical method based on screen-printed electrode and magnetic beads for trinucleotide repeat sequence d(CAG)n", New Journal of Chemistry, 2018, 42,9757-9763. (IF:3.201)

7        Hehong Lv, Ziqi Ren, Heng Liu, Ganbing Zhang*, Hanping He*, Xiuhua Zhang, Shengfu Wang. The turn-off fluorescent sensors based on thioether-linked bisbenzamide for Fe3+ and Hg2+. Tetrahedron, 2018, 74: 1668-1680. (IF:2.391)

8        Xiaoqian Zhu, Jiao Li, Hehong Lv, Hanping He*, Heng Liu, Xiuhua Zhang, and Shengfu Wang, Synthesis and characterization of a biofunctional nanoprobe for CGG trinucleotide repeat detection, RSC Adv., 2017,7, 36124-36131. (IF:2.936)

9        Xiaoqian Peng, Hanping He*, Jingping Xia, Zhaowen Lou, Gang Chang, Xiuhua Zhang, and Shengfu Wang,Visual detection and removal of mercury ions by a ferrocene derivative, Tetrahedron Letters, 2014, 55(18), 3541-3544. (IF:2.125)

10     Hanping He, Masaki Hagihara, Kazuhiko Nakatani. Small molecule affecting replication of trinucleotide repeat d(GAA)n, Chem. Eur. J, 2009, 15, 10641-10648. (Impact Factor: 5.454).

11 硕士生夏静平、彭小倩分别获 20142015年度湖北省优秀硕士学位论文。

12 国家发明专利授权5项。