杨桂春教授
  • 作者:佚名    发布日期:2010-05-05    点击率:

 

  杨桂春                

  教授    

学科专业有机化学    

办公电话027-50865322

Email Yangguichun@hubu.edu.cn

研究领域1、支载化合成及组合化学;2、不对称合成;3、精细化学品合成。    

个人简介:硕士,硕士生导师,中国化学会会员,湖北省化学化工学会有机化学专业委员会常务理事。    

主持科研项目    

1、枝化状PEG衍生物的合成及其应用研究(2010CDA019),湖北省自然科学基金重点项目,主持人    

2、新型支载化手性诱导试剂的合成及其应用研究(20772026), 国家自然科学基金,主持人。    

3、可溶性聚合物支载杂化合物的合成研究(2007ABA031),湖北省自然科学基金,主持人。    

4、可溶性聚合物支载手性试剂的制备及其应用研究(2003ABA065), 湖北省自然科学基金,主持人。    

5、聚乙二醇支载吡啶类叶立德组合合成中氮茚化合物库(2004D008),湖北省教育厅基金,主持人。    

6、微波辅助可溶性聚合物支载的有机反应研究(2001A01017),湖北省教育厅基金,主持人。    

7、可溶性聚合物支载手性试剂制备及应用研究,国家自然科学基金(20372019), 主要参与者(第二)。    

8、新型功能化聚合物微球的设计制备及其支载化有机合成研究(21042005),国家自然科学基,主要参与者(第二)    

9有机磷精细化学品研发,湖北兴发化工集团股份有限公司,300.00 万,2011.12015.12,重要参与。    

       科研获奖:    

1支载化有机合成研究获湖北省2007年度自然科学叁等奖(第三)。    

2生物活性物质的高立体选择性合成获湖北省2001年度自然科学叁等奖(第五)    

     

专利申请:    

1、陈祖兴, 李甲, 杨桂春, 卢翠芬. 线型聚苯乙烯支载手性噁唑烷-2-硒酮及其制备方法.ZL 201010265270.7.

2、卢翠芬, 陈祖兴, 夏德新, 胡富强, 杨桂春. 线型聚苯乙烯支载(4S)-噁唑烷-2-苯亚胺及其制备方法和用途. ZL201010241488.9.

3万亚东;陈祖兴;杨桂春;卢翠芬线型聚苯乙烯支载的(4S)-5,5-二取代基噁唑烷酮及其制备方法和用途,ZL 200610019140.9    

     

近年发表的主要科研论文    

1Zhang, J.S ., L.U, CF., Chen, Z.X., Li, Y., Yang G.C. Boron Enolates of A Hydantoin Chiral Auxiliary Derived From L-Phenylalanine: A Versatile Tool for Asymmetric Aldol ReactionsTetrahedron-Asymmetry,  2012, 23(1) :72-75.    

2Feng, C., Wang Q.,Y  Lu C. F., Yang G.C.., Chen  Z.X. Green Synthesis of Tetrahydrobenzo[B]Pyrans by Microwave Assisted Multi-Component One-Pot Reactions in PEG-400, Combinatorial Chemistry & High Throughput Screening, 2012, 15(1):100-103    

3He X.P., Lu C.F., Chen Z.X., Yang G.C. Synthesis of A New Chiral Auxiliary -Non-Cross-Linked Polystyrene-Supported Oxazolidine-2-Selone, Can. J. Chem., 2011, 89, 88-91.

4Gao M., Lu C.F., Yang G.C., Chen Z.X. A Novel Approach For Synthesis of 3- Amino-5-Aryl-2,5- Dihydropyridazines using Onium Salt as Soluble Support, Chinese Chemical Letters, 2011, 22, 823-826.

5Zhang L., Lu C.F., Yang G.C., Chen Z.X. Novel Synthesis of 2-Amino -3- Ethoxycarbonyl Benzopyrans with Onium Salt as Soluble Support,  Chem. Res. Chinese U., 2011, 27, 435-440.    

6Zhao P., Lu C.F., Yang G.C., Chen Z.X., Dong N.G., Shi J.W. Stereoselective Synthesis of Polysubstituted Cyclopropanes From Poly(Ethylene Glycol) Supported Pyridinium Ylide, Chem. Res. Chinese U., 2011, 27, 984-987.    

7Hu F.Q., Xia D.X., Lu C.F., Chen Z.X., Yang G.C. A New Non-Cross-Linked Polystyrene Supported 2-Phenylimino-2-Oxazolidine Chiral Auxiliary: Synthesis And Application in Asymmetric Alkylation Reactions. Eur. J. Org. Chem., 2010, 5552-5554.Highlighted In Synfacts 2011, 117    

8Lu C.F., Zhang L., Yang G.C, Chen Z.X. Task Specific Onium Salt as Soluble Support in Multicomponent Synthesis of 4-Aryl-2-Amino-3- Ethoxycarbonyl- Naphthopyrans. Chin. J. Chem., 2010, 28, 2469-2473.

9Xia D.X., Feng C., Lu C.F., Chen Z.X., Yang G.C. New Practical Synthesis of Tetrahydronquinolin- 2,5-Diones. Chem. Res. Chinese U., 2010, 26, 749-752.

10Feng C., Lu C.F., Chen Z.X., Dong N.G., Shi J.W., And Yang G.C. A Facile Synthesis of Tetrasubstituted 2,3-Dihydrofuran Derivatives using Poly(Ethylene glycol) as Soluble Support. J. Heterocyclic Chem., 2010, 47, 671-676.

11Zhou F.Y., Lu C.F., Chen Z.X. And Yang G.C. Stereoselective Synthesis of an Alarm Pheromone of Grematogaster Arts Using (S)-4-Benzyloxazolidinone as Chiral Auxiliary. Chem. Nat. Compd., 2010, 46, 83-85.

12Li J., Lu C.F., Chen Z.X., Yang G.C. Synthesis of Non-Crossed-Linked Polystyrene Supported (4S)-4- Substituted-4,5-Dihydrooxazoline. J.Chem.Res-S, 2010, 86-87.

13Li D.L., Lu C.F., Yang G.C., And Chen Z.X. Stereoselective Synthesis of Sex Pheromone of The Yellow Mealworm using (S)-4-Benzyloxazolidinone as Chiral Auxiliary. Chem. Nat. Compd., 2010, 46, 440-443.

14Lu C.F., Li D.L., Wang Q.Y., Yang G.C., Chen Z.X. Stereoselective Synthesis of Sex Pheromone (R)-4-Methyl-1-Nonanol: Non-Cross-Linked Polystyrene Supported Oxazolidinone as A Chiral AuxiliaryEur. J. Org. Chem. 2009, 1078-1081.

15Lu C.F., Zhang S.B., Li Y., Yang G.C., Chen Z.X. Stereoselective Synthesis of (R)-10- Methyltridecan -2-One, The Sex Pheromone of the Southerncorn Root worm, using (4S)-Benzylthiazolidinethione As A Chiral Auxiliary, Tetrahedron: Asymmetry, 2009, 20, 2267-2269.    

16Lu C.F., Nie J.Q., Yang G.C., Chen Z.X. An Improved Synthesis of SitophilureCan. J. Chem., 200987, 30-32. 

17Xie, H.W., Lu  C.F., Yang  G.C., Chen Z.X. Synthesis of 1,4-Benzodia zepine-2,5-Diones using An Ionic Liquid as A Soluble Support, Synthesis, 2009, 205-210.

18Lu C.F.,  Xie C., Chen Z.X., Yang  G.C. Synthesis of New Soluble Dendrimers on Poly(Ethylene Glycole) Sublayer,  Russ. J. Org. Chem., 2009, 45, 788 -791.    

19Yang J.H., Yang G.C., Lu C.F.,  Chen Z.X. Asymmetric Synthesis of (2R,5S)-2- Methyl-5-Hexanolide, The Sex Pheromone of Carpenter Bee Xylocopa Hirutissima, Tetrahedron- Asymmetry2008, 19, 2164-2166.

20Huang Y.L., Lu C.F., Chen Z.X., Yang GC. Traceless Synthesis of Quinazoline- 2,4-Diones By Curtius Rearrangement Reaction Using Poly(Ethylene Glycol) as Soluble-Polymeric Support, Journal of Heterocyclic Chemistry,  2007, 44, 1421-1424.    

21Yan X.Q., Yu J.J., Ye R.H., Chen Z.X., Yang GC. Synthesis of a Library of N-Substituted Methyl Aminocarbonyl Acetates using Poly(Ethylene Glycol) as Soluble Support, Letters in Organic Chemistry, 2007, 4 , 239-241.

22Peng H.D., Huang Y.L., Yang J.H., Chen Z.X., Yang GC. Traceless Synthesis of 3-N-Substituted -2-Thioxoquinazoline-4-Ones on A Soluble Polymeric Support, Combinatorial Chemistry & High Throughpu Screening, 2007, 10 , 257-260.

23Chen J.N., Yang G.C., Zhang H.Q., Chen ZX. Non-Cross-Linked Polystyrene Bound Reagents, Catalysts and Syntheses, Reactive and Functional Polymers, 2006, 66, 1434-1451.

24Yang G.C., Zhang H.Q., Huang Y.L., Chen Z.X.  Synthesis of Methyl N-Aryl Oxamate using Soluble Polymer SupportSynthetic Communications, 2006, 36, 611-619.

25Zhang H.Q., Yang G.C., Chen J.N., Chen Z.X. Synthesis of Thiophene Derivatives on Soluble Polymer-Support using Gewald Reaction, Synthesis, 2004, 18, 3055-3059.

26Yang G.C., Chen Z.X., Zhang H.Q. Clean Synthesis of An Array of N-Benzoyl–N’-Aryl Ureas using Polymer-Supported Reagents, Green Chemistry, 2003, 5, 441-442.

           

 

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